The genes with the clearest contribution to the risk for alcoholism andalcohol consumption are alcohol dehydrogenase 1B (ADH1B) andaldehyde dehydrogenase 2 (ALDH2; mitochondrial aldehydedehydrogenase), two genes central to the metabolism of alcohol (Figure 1)20. Alcohol is metabolized primarily in the liver, although thereis some metabolism in the upper GI tract and stomach. The first step […]
Monthly Archives: June 2022
Then, at certain points, the step costs increase to a higher amount. Both fixed and variable costs can take on this stair-step behavior. For instance, wages often act as a stepped variable cost when employees are paid a flat salary and a commission or when the company pays overtime. Further, when additional machinery or equipment […]